Can we predict who will thrive with brain stimulation for Parkinson's?

NCT ID NCT02360683

Completed Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 700 Parkinson's patients who received deep brain stimulation to see which factors predict a meaningful improvement in quality of life after 1, 3, and 5 years. Researchers analyzed clinical, imaging, and genetic data to identify who benefits most. The goal is to personalize treatment decisions and avoid unnecessary risks or costs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (subthalamic nucleus)
What this could lead to: If successful, this could help doctors better select which Parkinson's patients will benefit most from deep brain stimulation, improving outcomes and reducing unnecessary risks.
What could go wrong: This is an observational analysis of existing data, not a new treatment trial. It may not identify clear predictors, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE

Contacts and locations

Locations

CHU Hôpital NORD

Amiens, France
CHU Hôpital Pontchaillou

Rennes, France
CHU Purpan

Toulouse, France
CHU de Poitiers

Poitiers, France
CHU hôpital Nord Laennec

Nantes, France
Chu Ch.Nicolle

Rouen, France
Chu Gabriel-Montpied

Clermont-Ferrand, France
Devos

Lille, 59037, France
Fondation Ophtalmologique Adolphe de Rothschild

Paris, France
Hopital Pitie Salpetriere

Paris, France
Hôpital Central,

Nancy, France
Hôpital Pasteur

Nice, France
Hôpital Pierre Wertheimer

Bron, France
Hôpital de Hautepierre

Strasbourg, France
Hôpital de la Timone

Marseille, France

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