Can we predict who will thrive with brain stimulation for Parkinson's?

NCT ID NCT02360683

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 700 Parkinson's patients who received deep brain stimulation to see which factors predict a meaningful improvement in quality of life after 1, 3, and 5 years. Researchers analyzed clinical, imaging, and genetic data to identify who benefits most. The goal is to personalize treatment decisions and avoid unnecessary risks or costs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

deep brain stimulation (subthalamic nucleus)

What this could lead to

If successful, this could help doctors better select which Parkinson's patients will benefit most from deep brain stimulation, improving outcomes and reducing unnecessary risks.

What could go wrong

This is an observational analysis of existing data, not a new treatment trial. It may not identify clear predictors, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Hôpital NORD

    Amiens, France

  • CHU Hôpital Pontchaillou

    Rennes, France

  • CHU Purpan

    Toulouse, France

  • CHU de Poitiers

    Poitiers, France

  • CHU hôpital Nord Laennec

    Nantes, France

  • Chu Ch.Nicolle

    Rouen, France

  • Chu Gabriel-Montpied

    Clermont-Ferrand, France

  • Devos

    Lille, 59037, France

  • Fondation Ophtalmologique Adolphe de Rothschild

    Paris, France

  • Hopital Pitie Salpetriere

    Paris, France

  • Hôpital Central,

    Nancy, France

  • Hôpital Pasteur

    Nice, France

  • Hôpital Pierre Wertheimer

    Bron, France

  • Hôpital de Hautepierre

    Strasbourg, France

  • Hôpital de la Timone

    Marseille, France