A Million-Person quest to predict disease before it begins

NCT ID NCT07756320

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This observational study aims to understand how genes and the environment contribute to disease before it is even identified. Researchers will collect biological samples from 100,000 adult Mayo Clinic patients to build a comprehensive data repository. The goal is to predict biological processes that lead to disease, identify ways to stop disease progression early, and find potential targets for future therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to new ways to predict and prevent diseases before they become serious, and identify targets for future therapies.
What could go wrong: This is an observational study, so it won't test any treatment directly. It may take years to gather enough data, and findings may not lead to immediate medical breakthroughs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

inherited disease susceptibility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXPOSURE, ENVIRONMENTAL GENETIC PREDISPOSITION

Contacts and locations

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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Other studies related to the condition(s) this trial covers.