Smart dosing could transform Crohn's treatment in kids

NCT ID NCT05660746

Recruiting now Disease control Sponsor: Children's Hospital Medical Center, Cincinnati Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a computer program that calculates a personalized dose of infliximab based on blood tests can help children with Crohn's disease achieve deep remission better than standard dosing. About 180 children and young adults (ages 6–22) newly diagnosed with Crohn's will take part. The goal is to see if precision dosing leads to fewer symptoms and healed intestines without the need for steroids.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE

Contacts and locations

Locations

Children's Hospital of Los Angeles
RECRUITING

Los Angeles, California, 90027, United States
Children's Specialty Group
RECRUITING

Norfolk, Virginia, 23507, United States
Cincinnati Children's Hospital
RECRUITING

Cincinnati, Ohio, 45229, United States
Cleveland Clinic Children's Hospital
RECRUITING

Cleveland, Ohio, 44106, United States
Lucile Packard Children's Hospital Stanford
RECRUITING

Palo Alto, California, 94304, United States
Medical College of Wisconsin, Children's of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States
Nemours Children's Health System-Jacksonville
RECRUITING

Jacksonville, Florida, 32207, United States
Nemours Children's Health System-Wilmington
RECRUITING

Wilmington, Delaware, 19803, United States
Rady Children's Hospital San Diego
RECRUITING

San Diego, California, 92123, United States
Riley Hospital for Children
RECRUITING

Indianapolis, Indiana, 46202, United States

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