Gut-Brain link: prebiotics may improve sleep in poor sleepers
NCT ID NCT05239845
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking a prebiotic supplement for 56 days can improve sleep quality, gut health, thinking, immune function, and stress in healthy adults who report poor sleep. Sixty-eight volunteers will be randomly assigned to receive either a prebiotic blend or a placebo. The goal is to see if changing gut bacteria can lead to better rest.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prebiotic blend (milk fat globule membrane, lactoferrin, polydextrose, galactooligosaccharides)
What this could lead to
If it works, this could point toward a natural supplement to improve sleep quality and reduce stress without medication.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to people with sleep disorders. The effects may be modest or no better than placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northumbria Sleep Research, Northumbria University
Newcastle, United Kingdom
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Northumbria University
Newcastle, United Kingdom