Gut-Brain link: prebiotics may improve sleep in poor sleepers

NCT ID NCT05239845

Ongoing Symptom relief Sponsor: Northumbria University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a prebiotic supplement for 56 days can improve sleep quality, gut health, thinking, immune function, and stress in healthy adults who report poor sleep. Sixty-eight volunteers will be randomly assigned to receive either a prebiotic blend or a placebo. The goal is to see if changing gut bacteria can lead to better rest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prebiotic blend (milk fat globule membrane, lactoferrin, polydextrose, galactooligosaccharides)
What this could lead to: If it works, this could point toward a natural supplement to improve sleep quality and reduce stress without medication.
What could go wrong: This is a small, early-stage study in healthy volunteers, so results may not apply to people with sleep disorders. The effects may be modest or no better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SLEEP

Contacts and locations

Locations

Northumbria Sleep Research, Northumbria University

Newcastle, United Kingdom
Northumbria University

Newcastle, United Kingdom

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