Timing of radiation may cut brain cancer spread

NCT ID NCT05124236

First seen Mar 07, 2026 · Last updated Apr 28, 2026 · Updated 8 times

Summary

This study tests whether giving a single dose of radiation before surgery for brain metastases can lower the chance of cancer spreading in the brain's lining, compared to five doses after surgery. About 200 adults with brain tumors will be randomly assigned to one of the two approaches. The main goal is to see which timing better prevents leptomeningeal disease over 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Inselspital, Universitätsklinik für Radio-Onkologie

    RECRUITING

    Bern, Freiburgstrasse, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Aarau

    RECRUITING

    Aarau, Canton of Aargau, 5001, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Graubünden

    RECRUITING

    Chur, 7000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital St. Gallen

    RECRUITING

    Sankt Gallen, 9000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Winterthur

    RECRUITING

    Winterthur, 8400, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Knappschaft Kliniken, Universitätsklinikum Bochum GmbH

    RECRUITING

    Bochum, Germany

    Contact Email: •••••@•••••

  • Luzerner Kantonsspital

    RECRUITING

    Lucerne, 6000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tirol Kliniken Innsbruck

    ACTIVE_NOT_RECRUITING

    Innsbruck, 6020, Austria

  • UKGM-Giessen

    RECRUITING

    Giessen, Germany

    Contact Email: •••••@•••••

  • Universitätsklinikum Schleswig Holstein

    RECRUITING

    Kiel, 24103, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.