Could a Parkinson's drug help restore joy in depression?
NCT ID NCT05355337
First seen Apr 28, 2026 · Last updated Apr 30, 2026 · Updated 2 times
Summary
This study tested whether pramipexole, a drug used for Parkinson's disease, can help people with depression who have lost the ability to feel pleasure (anhedonia). 85 adults with depression and significant anhedonia took pramipexole or a placebo alongside their usual antidepressant. The goal was to see if the drug improves pleasure and motivation, and to better understand the brain changes involved.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Region Skåne
Lund, Skåne County, 221 85, Sweden
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