Could a Parkinson's drug help treat a key symptom of depression?

This study tested whether pramipexole, a drug used for Parkinson's disease, can help people with depression who still have trouble feeling pleasure or motivation despite taking standard antidepressants. 85 adults with depression and significant anhedonia took either pramipexole or a placebo alongside their usual medication for 9 weeks. The goal was to see if the drug could improve anhedonia symptoms and help move toward more personalized depression treatment.