Experimental drug poziotinib tested for rare lung cancer mutations

NCT ID NCT03066206

First seen Nov 11, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This study tested a drug called poziotinib in 93 people with advanced non-small cell lung cancer that has specific changes in the EGFR or HER2 genes. The goal was to see if the drug could shrink tumors. The study was stopped early, but results may help guide future treatments for these rare mutations.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.