Could a simple pill improve recovery after hip replacement?

NCT ID NCT06832878

Recruiting now Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study tests whether taking oral tranexamic acid for three days after hip replacement surgery can reduce pain, swelling, and help patients walk sooner. About 101 adults with end-stage osteoarthritis will receive the drug or placebo. The goal is to see if this simple pill improves recovery and reduces complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tranexamic acid (oral)
What this could lead to: If it works, this could mean a simple pill after hip replacement reduces pain, swelling, and speeds up recovery without needing extra injections.
What could go wrong: This is a small, early-phase study (101 people) testing a drug already used in other settings. The benefits may be modest, and side effects like blood clots are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPLASTY

Contacts and locations

Locations

Mayo Clinic in Arizona
RECRUITING

Scottsdale, Arizona, 85259, United States

More trials for these conditions

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