Botox for bladder: scientists probe hidden microbiome link

NCT ID NCT07025044

Recruiting now Knowledge-focused Sponsor: Alexis Dieter Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how Botox injections for overactive bladder affect the community of bacteria in the urinary tract of postmenopausal women. Researchers will collect urine samples before and after treatment to see if changes in the microbiome relate to treatment success or side effects like urinary tract infections. The goal is to learn more about who benefits most from Botox and why some women develop infections afterward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: onabotulinum toxin type A (Botox)
What this could lead to: If successful, this study could help doctors understand why some women get urinary tract infections after Botox treatment for overactive bladder.
What could go wrong: This is a small, early feasibility study with only 40 participants, so results may not apply to all women. It is designed to test methods, not to prove treatment effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

overactive bladder Urinary Incontinence, Urge

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER (OAB) URGE INCONTINENCE

Contacts and locations

Locations

MedStar Urogynecology Clinic
RECRUITING

Washington D.C., District of Columbia, 20010, United States

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