Could 5 days of antibiotics cut infections after pancreatic surgery?

NCT ID NCT06123169

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two antibiotic strategies in 326 adults undergoing pancreatic surgery who had a bile duct stent placed before surgery. One group gets antibiotics only during surgery, the other gets them for 5 days after. The goal is to see if the longer course reduces surgical site infections, including pancreatic leaks. The trial is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Piperacillin-tazobactam (an antibiotic)
What this could lead to
If successful, this could establish a standard antibiotic regimen to prevent serious infections after pancreatic surgery in patients with a prior bile duct stent.
What could go wrong
This is a Phase 3 trial, but it has not yet started recruiting. The benefit may be small, and antibiotics carry risks like allergic reactions or drug-resistant infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de ROUEN

    Rouen, 76031, France

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