Radiation before pancreatic surgery may prevent dangerous leaks

NCT ID NCT07370987

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether giving a short course of radiation before pancreatic surgery can prevent a common and serious complication called pancreatic fistula. About 50 patients with a high risk of this complication will receive two doses of radiation before their surgery. Researchers will then track how many patients avoid a fistula within 90 days after the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

stereotactic radiotherapy

What this could lead to

If it works, this could reduce a serious complication after pancreatic surgery, making recovery safer for patients.

What could go wrong

This is a small, early-phase trial with only 50 participants and no comparison group, so results may not be conclusive. Radiotherapy also carries risks like radiation toxicity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pancreatic Fistula

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of HPB Surgery, Hospital Pitié Salpétrière

    RECRUITING

    Paris, 75013, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••