Ultrasound of the portal vein may reveal fluid tolerance in critical care

NCT ID NCT07131228

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study investigates whether a temporary increase in tidal volume (from 6 to 8 mL/kg) can help predict fluid tolerance in critically ill patients on mechanical ventilation. The researchers will use Doppler ultrasound to measure changes in the portal vein's pulsatility index, a marker of venous congestion. The goal is to see if this test can identify patients who might be harmed by additional fluids, potentially improving fluid management in the ICU.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive way to predict whether giving fluids will harm or help critically ill patients.
What could go wrong
This is a small, early-stage study (60 participants) focused on a specific ICU population. The findings may not apply to other patients or settings.

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Conditions

The condition(s) this trial relates to.

Hyperemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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