ICU fluid study could change how doctors treat vein congestion

NCT ID NCT07499401

Recruiting now Knowledge-focused Sponsor: Università Politecnica delle Marche Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how giving fluids affects the smallest blood vessels in critically ill patients with venous congestion. Researchers will give a small amount of fluid and check blood flow in the mouth before, right after, and 30 minutes later. The goal is to see if fluids help or hurt these patients, which could guide better treatment in the ICU.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fluid challenge (intravenous fluids)
What this could lead to: If successful, this could help doctors decide when to give fluids to ICU patients with venous congestion, potentially avoiding harm.
What could go wrong: This is a small, early observational study with only 30 participants, so results may not apply broadly. It does not test a new treatment.

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Conditions

The condition(s) this trial relates to.

Hyperemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MICROCIRCULATION VENOUS CONGESTION VOLUME EXPANSION

Contacts and locations

Locations

AOU delle Marche
RECRUITING

Ancona, Italy, 60123, Italy

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