Special stent fails to beat standard for tricky heart blockage

NCT ID NCT03508219

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new type of stent (BiOSS LIM C) designed for blockages at the left main coronary artery fork. The trial enrolled 130 people with severe blockages. Unfortunately, the new stent did not work as well as the standard stent, and the study was stopped early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BiOSS LIM C stent (a drug-coated stent for bifurcation blockages)

What this could lead to

If it had succeeded, this could have pointed toward a better treatment for complex left main coronary blockages.

What could go wrong

The trial was terminated early because the new stent was not as effective as the standard stent. This is an early-stage device study with limited participants, so results may not apply broadly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Centre FRA-001

    Aix-en-Provence, France

  • Research Centre FRA-002

    Saint-Denis, France

  • Research Centre FRA-003

    Grenoble, France

  • Research Centre FRA-004

    Bron, France

  • Research Centre ITA-001

    Naples, Italy

  • Research Centre ITA-002

    Ragusa, Italy

  • Research Centre ITA-003

    Syracuse, Italy

  • Research Centre PL-001

    Warsaw, Poland

  • Research Centre PL-002

    Zabrze, Poland

  • Research Centre PL-003

    Zabrze, Poland

  • Research Centre PL-004

    Olsztyn, Poland

  • Research Centre PL-005

    Poznan, Poland

  • Research Centre PL-006

    Katowice, Poland

  • Research Centre PL-007

    Krakow, Poland

  • Research Centre PL-008

    Warsaw, Poland