One procedure to replace lifelong blood thinners? new trial tests dual heart fix for stroke survivors
NCT ID NCT06212674
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single procedure that combines two heart treatments—pulmonary vein isolation (to correct irregular heartbeat) and left atrial appendage occlusion (to block a clot-prone area)—can prevent future strokes and major bleeding better than standard blood thinners. The trial enrolls 240 adults who recently had a stroke and have atrial fibrillation. Participants are randomly assigned to the combined procedure, the occlusion procedure alone, or continued medication. The goal is to see if the combined approach is at least as effective as medication, with fewer bleeding risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Procedure: pulmonary vein isolation (PVI) plus left atrial appendage occluder (LAAO) implantation
- What this could lead to
- If successful, this combined procedure could offer a one-time treatment to reduce stroke risk and bleeding complications compared to lifelong blood thinners.
- What could go wrong
- This is a Phase 4 trial with 240 participants, so results are preliminary. The procedure carries risks like bleeding, infection, or device complications, and may not be superior to standard medication.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ATRIAL FIBRILLATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Silesian Center for Heart Disease
RECRUITINGZabrze, Upper Silesia, 41-800, Poland
-
Upper-Silesian Medical Center
RECRUITINGKatowice, Upper Silesia, 40-635, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping the brain to restore swallowing after stroke?
- Can Brain-Triggered stimulation reawaken arms after stroke?
- Can lifestyle choices after a stroke extend life and prevent a second one?
- Can Clot-Removing devices improve stroke recovery?
- A tiny neck implant could catch Stroke-Causing clots before they reach the brain
- Can virtual games retrain the brain to restore balance?