Can getting kids moving sooner in the ICU shorten their time on a ventilator?
NCT ID NCT04989790
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tests a program called PICU Up! that helps critically ill children start moving earlier while in the pediatric intensive care unit. The program includes daily activity plans, better sedation management, and family involvement. Researchers want to see if this approach reduces how long children need a breathing machine and improves their overall recovery. The trial will involve 1,440 children across 10 U.S. hospitals.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital at Dartmouth: Geisel School of Medicine
RECRUITINGLebanon, New Hampshire, 03756, United States
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Children's Hospital of Wisconsin: Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Hennepin Healthcare: University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55415, United States
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Janet Weis Children's Hospital: Geisinger Commonwealth School of Medicine
RECRUITINGDanville, Pennsylvania, 17822, United States
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Johns Hopkins Hospital
ACTIVE_NOT_RECRUITINGBaltimore, Maryland, 21287, United States
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Nemours Children's Hospital of the Nemours Foundation
RECRUITINGOrlando, Florida, 32827, United States
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Norton Children's Hospital: University of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
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Texas Children's Hospital: Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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UNC Children's: University of North Carolina
RECRUITINGChapel Hill, North Carolina, 27514, United States
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Valley Children's Hospital
RECRUITINGMadera, California, 93636, United States
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West Virginia University Medicine Children's: West Virginia University
RECRUITINGMorgantown, West Virginia, 26506, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PICU Up! early mobility program
What this could lead to
If effective, this program could become a new standard of care to help critically ill children recover faster and with fewer complications.
What could go wrong
This is a pragmatic trial testing a complex intervention across many hospitals, so results may vary. The study is not designed to prove a cure, only to improve recovery.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.