Hand pain relief without surgery? physical therapy shows promise for carpal tunnel

NCT ID NCT04329247

Completed Symptom relief Sponsor: Universidad Europea de Madrid Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a specific physical therapy technique called median nerve neural mobilization can reduce pain in people with carpal tunnel syndrome. 74 participants were randomly assigned to receive the therapy or no treatment. The main goal was to measure pain reduction using a standard pain scale, and the researchers also looked at hand and arm function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: median nerve neural mobilization (a manual therapy maneuver)
What this could lead to: If it works, this could offer a non-surgical, drug-free option to ease pain and improve hand function for people with carpal tunnel syndrome.
What could go wrong: This is a small, completed trial with only 74 participants. The results may not apply to everyone, and the benefit over no treatment might be modest.

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Conditions

The condition(s) this trial relates to.

agnosia carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARPAL TUNNEL SYNDROME

Contacts and locations

Locations

Ciudad Hospitalaria Enrique Tejera

Valencia, Carabobo, 2001, Venezuela

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