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Laser light before muscle shocks: a new way to cut fatigue?

NCT ID NCT07790016

Symptom relief Sponsor: Federal University of Rio Grande do Sul Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Sep 01, 2026 · Updated 3 times

Summary

This trial tests whether shining low-level laser light on the thigh muscles before a session of electrical muscle stimulation can reduce fatigue, soreness, and muscle damage. Healthy adults aged 18 to 40 receive either real or sham light therapy on each leg, then undergo a 20-minute electrical stimulation protocol. Researchers measure muscle strength, pain, and function immediately after and over the next three days. The goal is to see if light therapy can make electrical stimulation more comfortable and effective for rehabilitation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Photobiomodulation therapy (low-level laser) applied to the thigh muscles before electrical stimulation
What this could lead to
If it works, light therapy could become a simple way to reduce muscle fatigue and soreness from electrical stimulation, improving rehabilitation outcomes.
What could go wrong
This is a small pilot study with only 12 participants, so results may not apply broadly. The effect of light therapy on muscle fatigue is still uncertain and conflicting in previous research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Nov 2022

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy male and female adults aged between 18 and 40 years. * Engaging in regular physical activity (minimum of twice a week). * No history of hospitalization for COVID-19 in the past 12 months. * Demonstrated ability to tolerate neuromuscular electrical stimulation (NMES). * Capable of fully understanding and complying with the experimental protocol and procedures. Exclusion Criteria: * Presence of any sensory impairments or neurological alterations. * Ingestion of caffeine, coffee, energy drinks, or other stimulants in the 12 hours preceding the testing sessions. * Body Mass Index (BMI) greater than 30 kg/m². * Any medical contraindication to performing maximal physical exertion or presenting an abnormal cardiovascular/blood pressure response after maximal effort.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delayed onset muscle soreness (DOMS) Muscle damage Muscle fatigue (C23.888.592.612.612) Neuromuscular electrical stimulation (NMES) Photobiomodulation (PBM)

Contacts and locations

Locations

  • Laboratório de Pesquisa do Exercício

    Porto Alegre, Rio Grande do Sul, 90690200, Brazil

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