Turmeric's curcumin vs. ibuprofen: a natural path to faster muscle recovery?
NCT ID NCT07785986
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This trial tests whether a natural compound from turmeric, curcumin, can ease muscle soreness and damage after intense exercise as effectively as the common painkiller ibuprofen. Physically active women will take either curcumin, ibuprofen, or a placebo before and after a demanding exercise routine. Researchers will measure muscle pain, performance, and blood markers of inflammation and oxidative stress to see if curcumin offers a safer, natural alternative for recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oral curcumin supplement
- What this could lead to
- If curcumin works as well as ibuprofen, it could offer a natural, safer option for easing post-exercise muscle soreness and speeding recovery.
- What could go wrong
- This is a small early-stage trial, so results may not apply broadly. Curcumin may not match ibuprofen's effects, and individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
36 people
The number who actually took part.
- Started
-
Jan 2026
- Finished
-
Aug 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 30 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Healthy physically active women. Age within the predefined study range. Regular participation in physical activity for at least 6 months before enrollment. Ability to perform the eccentric exercise protocol. Written informed consent provided before participation. Exclusion Criteria: Current musculoskeletal injury or pain affecting exercise performance. History of cardiovascular, metabolic, neurological, renal, hepatic, or inflammatory disease. Pregnancy or breastfeeding. Current use of anti-inflammatory drugs, antioxidant supplements, or other nutritional supplements that could interfere with study outcomes. Known allergy or intolerance to curcumin, turmeric, ibuprofen, or study ingredients. Smoking or excessive alcohol consumption. Participation in another clinical trial during the study period. Any condition considered by the investigators to compromise participant safety or protocol compliance.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Campus of Soria
Soria, 42004, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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