Could a glutathione booster help soccer players recover between matches?
NCT ID NCT07690124
First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time
Summary
This study tests whether a daily supplement called S-Acetyl Glutathione helps highly trained soccer players recover muscle function and reduce inflammation after a 90-minute match. Twenty elite players take either 200 mg, 500 mg, or a placebo for 11 days. Researchers measure muscle damage markers, strength, and sprint performance at 24, 48, and 72 hours after the game.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- S-Acetyl Glutathione (dietary supplement)
- What this could lead to
- If it works, this could point toward a simple supplement to help athletes recover faster between games.
- What could go wrong
- This is a small early study in elite soccer players, so results may not apply to other people or sports. The supplement may not speed recovery or reduce soreness.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 29 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * participation at elite (top three division leagues) for ≥ 4 years * no recent history of febrile illness, musculoskeletal problems and metabolic diseases * no consumption of medications and performance-enhancing supplements (including anti-inflammatory, antioxidants, vitamins and multivitamin supplements) for at least 6 months prior to the study * participation in at least 5 training sessions and 1 match per week * non-smokers Exclusion Criteria: * musculoskeletal injury * consumption of medication and performance-enhancing supplements * illness during the course of the study * loss of follow-up measurements
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Physical Education and Sport Science, University of Thessaly
Trikala, Karies, 42100, Greece
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