Experimental combo aims to help leukemia patients reach transplant

NCT ID NCT07297173

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether giving chemotherapy followed by an infusion of immune cells from a partially matched donor can help patients with relapsed or refractory leukemia get to a stem cell transplant. Only 5 participants will be enrolled to check safety and side effects like graft-versus-host disease and infections. The goal is to find a better way to control the disease long enough for a transplant to work.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HLA-mismatched G-CSF mobilized peripheral blood mononuclear cells (donor immune cells)

What this could lead to

If successful, this approach could help more patients with hard-to-treat leukemia get to a stem cell transplant and possibly achieve long-term disease control.

What could go wrong

This is a very early Phase 1 trial with only 5 people, so safety and effectiveness are not yet known. There are serious risks like graft-versus-host disease and severe infections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

leukemia refractory hematologic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology, the Fifth Medical Center of Chinese PLA General Hospital

    RECRUITING

    Beijing, 100071, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact