New hope for tough leukemias: experimental drug combo enters human testing

NCT ID NCT04874480

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 26 times

Summary

This early-stage trial tests a drug called tegavivint, combined with decitabine, in adults with leukemia that has come back or stopped responding to standard treatments. The goal is to find the safest dose and see if the combination can control the disease. Only 9 participants are enrolled, so results are very preliminary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE MYELOID LEUKEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

acute myeloid leukemia leukemia refractory hematologic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.