New Triple-Drug combo aims to wipe out Hard-to-Treat leukemia

NCT ID NCT06644183

First seen Feb 17, 2026 · Last updated May 01, 2026 · Updated 5 times

Summary

This study tests whether adding a new drug called roginolisib to two standard drugs (venetoclax and rituximab) can safely make chronic lymphocytic leukemia (CLL) disappear to undetectable levels in patients whose cancer has returned or not responded to prior treatments. About 64 adults with relapsed or refractory CLL who have already tried at least two other therapies will participate. The goal is to see if this combination can achieve a deep remission, though ongoing monitoring and potential future treatment may still be needed.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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