New combo ablation aims to stop AFib in its tracks

NCT ID NCT07171463

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new approach for treating paroxysmal atrial fibrillation (a type of irregular heartbeat). It combines two procedures: pulsed-field ablation to isolate the pulmonary veins, plus targeted thermal ablation of a nerve cluster near the heart. The goal is to see if adding the thermal step reduces AFib recurrence and dangerous slow heart rates during the procedure. Twenty adults with documented paroxysmal AFib will be randomly assigned to receive either the standard ablation or the combo treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pulsed-field ablation and radiofrequency ablation

What this could lead to

If successful, this combination approach could reduce AFib recurrence and the need for repeat procedures.

What could go wrong

This is a very small early-stage trial with only 20 participants, so results may not apply broadly. The added thermal ablation also carries risks like nerve damage or heart tissue injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Joseph's Heart Rhythm Center

    RECRUITING

    Rzeszów, Podkarpackie Voivodeship, 35-623, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••