Brain tumor breakthrough? shorter radiation shows promise for GBM patients

This study is for older adults (50+) with aggressive brain tumors (GBM) who are not healthy enough for surgery. It tests whether a shorter course of high-dose radiation, guided by a PET scan to target the most active tumor areas, can help them live longer compared to the current standard treatment. About 108 participants will be randomly assigned to either the new short radiation or the standard 3-week radiation, both with chemotherapy. The goal is to see if the shorter treatment improves survival at one year while reducing side effects.