Can digestive enzymes ease Post-Pancreatitis symptoms? new trial aims to find out

NCT ID NCT06477159

Recruiting now Symptom relief Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 6-month course of pancrelipase (CREON) can improve digestive symptoms in people who have exocrine pancreatic insufficiency (EPI) after an acute pancreatitis attack. About 30 adults with confirmed EPI and moderate-to-severe symptoms will take the enzyme replacement and report their symptom changes over time. The goal is to see if this treatment eases discomfort and improves quality of life.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXOCRINE PANCREATIC INSUFFICIENCY

Contacts and locations

Locations

New York University Langone Medical Center
WITHDRAWN

New York, New York, 10016, United States
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
University of Illinois Chicago
RECRUITING

Chicago, Illinois, 60612, United States
University of Minnesota
NOT_YET_RECRUITING

Minneapolis, Minnesota, 55455, United States
University of Pittsburgh
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

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