Lab-Grown tumor avatars could personalize breast cancer treatment

NCT ID NCT06459791

Recruiting now Disease control Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new approach for metastatic breast cancer patients. Doctors take a biopsy of a tumor and grow it in the lab to create a 'tumorogram'—a map showing which drugs might work best. Then, patients receive a treatment chosen based on this map. The goal is to see if this personalized approach leads to better tumor shrinkage within 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized tumorogram-based therapy
What this could lead to: If successful, this approach could help doctors choose more effective treatments for metastatic breast cancer patients, potentially improving response rates.
What could go wrong: This is an early proof-of-concept study with only 110 participants, so results may not apply to all patients. The tumorogram may not always predict treatment success.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC BREAST CANCER

Contacts and locations

Locations

Hôpital Saint-Louis - AP-HP Senopole
NOT_YET_RECRUITING

Paris, 75010, France
Institut Curie
RECRUITING

Paris, 75005, France
Institut Curie
RECRUITING

Saint-Cloud, 92210, France

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