Scientists reprogram Patients' own cells to hunt cancer

This early-stage study tested a personalized cancer treatment that modifies a patient's own immune cells to recognize and attack their specific tumor mutations. The trial enrolled 8 adults with advanced solid tumors (including ovarian, lung, pancreatic, and colorectal cancers) who had exhausted standard treatments. Researchers collected patients' immune cells, genetically engineered them to target cancer mutations, then reinfused them to see if they were safe and could persist in the body.