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New surgery approach may help kids with down syndrome breathe better at night

NCT ID NCT05508971

Recruiting now Disease control Sponsor: Oregon Health and Science University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study compares personalized surgery guided by a special camera during sleep (DISE) to standard tonsil and adenoid removal for treating obstructive sleep apnea in 303 children with Down syndrome, ages 2 to 17. Sleep apnea is very common in these children and standard surgery often fails. The goal is to see if tailoring surgery to each child's unique airway blockages leads to better sleep and health outcomes.

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Conditions

The condition(s) this trial relates to.

Down syndrome obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DOWN SYNDROME OBSTRUCTIVE SLEEP APNEA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital

    TERMINATED

    Cincinnati, Ohio, 45229, United States

  • Colorado Children's Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

    Contact

  • EVMS Medical School

    RECRUITING

    Norfolk, Virginia, 23507, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

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