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Smart antibody monitoring could prevent pemphigus Flare-Ups

NCT ID NCT05898308

Recruiting now Disease control Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a personalized approach to treating pemphigus, a rare blistering skin disease. Instead of waiting for a relapse, doctors will use blood tests to measure specific antibodies and give extra rituximab infusions only when those levels rise. The goal is to prevent flare-ups and reduce the need for steroids. About 133 adults with newly diagnosed moderate-to-severe pemphigus will take part.

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Conditions

The condition(s) this trial relates to.

pemphigus pemphigus foliaceus pemphigus vulgaris skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DERMATOLOGIC DISEASE PEMPHIGUS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ap-Hm Hopital Nord

    NOT_YET_RECRUITING

    Marseille, 13915, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hm La Timone

    NOT_YET_RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hp Bichat

    NOT_YET_RECRUITING

    Paris, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hp Henri Mondor

    NOT_YET_RECRUITING

    Créteil, 94010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hp Hopital Avicennes

    NOT_YET_RECRUITING

    Bobigny, 93000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hp Hopital Cochin

    NOT_YET_RECRUITING

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ap-Hp Pitie Salpetriere

    NOT_YET_RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-••••

    Contact

  • Ap-Hp Saint Louis

    NOT_YET_RECRUITING

    Paris, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CH NIORT

    RECRUITING

    Niort, 79000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU CAEN

    RECRUITING

    Caen, 14033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ch Argenteuil

    RECRUITING

    Argenteuil, 51000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ch Dunkerque

    RECRUITING

    Dunkirk, 59385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ch Le Mans

    RECRUITING

    Le Mans, 72037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chr Orleans

    RECRUITING

    Orléans, 45067, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Amiens

    RECRUITING

    Amiens, 80054, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Angers

    RECRUITING

    Angers, 49100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Bordeaux

    RECRUITING

    Bordeaux, 33076, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Brest

    RECRUITING

    Brest, 29200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Clermont-Ferrand

    RECRUITING

    Clermont-Ferrand, 63100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Dijon

    RECRUITING

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Guadeloupe

    RECRUITING

    Pointe-à-Pitre, 97159, Guadeloupe

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Lille

    RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Limoges

    RECRUITING

    Limoges, 87000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Montpellier

    RECRUITING

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Nantes

    RECRUITING

    Nantes, 44000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Reims

    NOT_YET_RECRUITING

    Reims, 51092, France

    Contact Phone: •••-•••-••••

    Contact

  • Chu Rennes

    RECRUITING

    Rennes, 35000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Rouen

    RECRUITING

    Rouen, 76031, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Saint-Etienne

    RECRUITING

    Saint-Etienne, 42270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Toulouse

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chu Tours

    RECRUITING

    Tours, 37000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Gh Le Havre

    RECRUITING

    Le Havre, 76290, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hcl Edouard Herriot

    NOT_YET_RECRUITING

    Lyon, 69003, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hcl Lyon Sud

    NOT_YET_RECRUITING

    Pierre-Bénite, 69310, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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