One-Size-Fits-All oxygen may be outdated: new trial tests personalized targets
NCT ID NCT07536984
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether giving each patient on a ventilator a personalized oxygen target (based on their unique health data) leads to better outcomes than standard care. Researchers will compare death rates and time spent on the ventilator between the two groups. The trial involves 3,000 adults in intensive care units at Vanderbilt.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
personalized SpO2 target (oxygen level goal)
What this could lead to
If it works, this could show that tailoring oxygen levels to each patient improves survival and reduces time on a ventilator.
What could go wrong
This is an early-stage study testing a new approach. The personalized targets are based on a statistical model, which may not work for everyone. There is also a risk that the model's recommendations could lead to worse outcomes in some patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States