Blood test may replace biopsies for breast cancer patients

NCT ID NCT02965755

Ongoing Knowledge-focused Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study at Johns Hopkins is testing whether genetic information from a blood sample can match what is found in a tumor biopsy for people with metastatic breast cancer. Researchers will use the results to suggest personalized treatment options. The goal is to see if a simple blood test can guide therapy when a biopsy is not possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized genetic profiling and treatment recommendation
What this could lead to: If successful, this could show that a simple blood test can replace tumor biopsies for guiding treatment decisions in metastatic breast cancer.
What could go wrong: This is an early-stage observational study, not a treatment trial. It may not prove that blood-based profiling improves outcomes or is feasible for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC BREAST CANCER

Contacts and locations

Locations

Allegheny Health Network Cancer Institute

Pittsburgh, Pennsylvania, 15212, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Baltimore, Maryland, 21287-0013, United States

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