New device aims to tackle deadly lung clots

NCT ID NCT06588634

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a device called FlowTriever that removes blood clots from the lungs in people with a severe, high-risk pulmonary embolism. About 200 participants will be randomly assigned to get either the device or standard care. The goal is to see if the device reduces death, cardiac arrest, major bleeding, and the need for life support.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FlowTriever System (a device that removes blood clots from the lungs)

What this could lead to

If successful, this could provide a more effective treatment for high-risk pulmonary embolism, potentially reducing death and complications.

What could go wrong

This is a relatively early-stage study with 200 participants. The device may not prove better than standard care, and there are risks like major bleeding or need for additional procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allegheny General Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

    Contact

  • Besançon University Hospital

    RECRUITING

    Besançon, 25030, France

    Contact

  • CHU Nîmes Caremeau

    RECRUITING

    Nîmes, France

    Contact

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

  • HCA Medical City Heart & Spine

    RECRUITING

    Dallas, Texas, 75039, United States

    Contact

  • HCA Methodist Health San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

  • HCA Tristar/Centennial

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • Hopital Arnaud de Villeneuve, Montpellier

    RECRUITING

    Montpellier, France

    Contact

  • Hospital Universitari Vall d'Hebron, Barcelona

    RECRUITING

    Barcelona, Spain

    Contact

  • Hospital Universitario La Paz Madrid

    RECRUITING

    Madrid, 28046, Spain

    Contact

  • Hôpital Européen Georges-Pompidou, Paris

    RECRUITING

    Paris, France

    Contact

  • Klinikum Chemnitz

    RECRUITING

    Chemnitz, Germany

    Contact

  • Munich LMU

    RECRUITING

    München, Germany

    Contact

  • Northwell Health

    RECRUITING

    Bay Shore, New York, 11706, United States

    Contact

  • Orlando Health Regional Medical Center

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact

  • Royal Free Hospital London

    RECRUITING

    London, United Kingdom

    Contact

  • SUNY, The University at Buffalo

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact

  • Sarasota Memorial Hospital

    RECRUITING

    Sarasota, Florida, 34239, United States

    Contact

  • Summa Akron

    RECRUITING

    Akron, Ohio, 44304, United States

    Contact

  • UPHS Penn Health System

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact

  • University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

    Contact

  • University of Mississippi Medical Center

    RECRUITING

    Jackson, Mississippi, 39216, United States

    Contact

  • Universitätsklinik Regensburg

    RECRUITING

    Regensburg, Germany

    Contact

  • Universitätsklinikum Carl Gustav Carus an der TU Dresden

    RECRUITING

    Dresden, Germany

    Contact

  • Universitätsmedizin Mainz

    RECRUITING

    Mainz, 55131, Germany

    Contact

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact