New device aims to tackle deadly lung clots

NCT ID NCT06588634

Recruiting now Disease control Sponsor: Inari Medical Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study is testing a device called FlowTriever that removes blood clots from the lungs in people with a severe, high-risk pulmonary embolism. About 200 participants will be randomly assigned to get either the device or standard care. The goal is to see if the device reduces death, cardiac arrest, major bleeding, and the need for life support.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FlowTriever System (a device that removes blood clots from the lungs)
What this could lead to: If successful, this could provide a more effective treatment for high-risk pulmonary embolism, potentially reducing death and complications.
What could go wrong: This is a relatively early-stage study with 200 participants. The device may not prove better than standard care, and there are risks like major bleeding or need for additional procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM PULMONARY THROMBOEMBOLISM

Contacts and locations

Locations

AdventHealth Orlando
RECRUITING

Orlando, Florida, 32803, United States
Allegheny General Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Besançon University Hospital
RECRUITING

Besançon, 25030, France
CHU Grenoble Alpes
RECRUITING

La Tronche, 38700, France
CHU Nîmes Caremeau
RECRUITING

Nîmes, France
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
HCA Medical City Heart & Spine
RECRUITING

Dallas, Texas, 75039, United States
HCA Methodist Health San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
HCA Tristar/Centennial
RECRUITING

Nashville, Tennessee, 37203, United States
Hopital Arnaud de Villeneuve, Montpellier
RECRUITING

Montpellier, France
Hospital Universitari Vall d'Hebron, Barcelona
RECRUITING

Barcelona, Spain
Hospital Universitario La Paz Madrid
RECRUITING

Madrid, 28046, Spain
Hôpital Européen Georges-Pompidou, Paris
RECRUITING

Paris, France
Klinikum Chemnitz
RECRUITING

Chemnitz, Germany
Munich LMU
RECRUITING

München, Germany
Northwell Health
RECRUITING

Bay Shore, New York, 11706, United States
Orlando Health Regional Medical Center
RECRUITING

Orlando, Florida, 32806, United States
Royal Free Hospital London
RECRUITING

London, United Kingdom
SUNY, The University at Buffalo
RECRUITING

Buffalo, New York, 14203, United States
Sarasota Memorial Hospital
RECRUITING

Sarasota, Florida, 34239, United States
Summa Akron
RECRUITING

Akron, Ohio, 44304, United States
UPHS Penn Health System
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
UPMC
RECRUITING

Pittsburgh, Pennsylvania, 152123, United States
University Hospital Basel
RECRUITING

Basel, 4031, Switzerland
University of Mississippi Medical Center
RECRUITING

Jackson, Mississippi, 39216, United States
Universitätsklinik Regensburg
RECRUITING

Regensburg, Germany
Universitätsklinikum Carl Gustav Carus an der TU Dresden
RECRUITING

Dresden, Germany
Universitätsmedizin Mainz
RECRUITING

Mainz, 55131, Germany
Yale University
RECRUITING

New Haven, Connecticut, 06519, United States

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