New trial tests if adding chemo before and after surgery boosts survival for abdominal spread of colorectal cancer

NCT ID NCT02758951

First seen Apr 02, 2026 · Last updated Jun 17, 2026 · Updated 17 times

Summary

This study looks at whether giving chemotherapy before and after surgery (plus heated chemo inside the abdomen) helps people with colorectal cancer that has spread to the lining of the belly live longer compared to having surgery alone. About 358 adults with resectable tumors are taking part. The main goal is to see if the combined approach improves overall survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Amsterdam University Medical Centre, Location VUMC

    Amsterdam, Netherlands

  • Catharina Hospital

    Eindhoven, Netherlands

  • Erasmus University Medical Centre

    Rotterdam, Netherlands

  • Netherlands Cancer Institute

    Amsterdam, Netherlands

  • Radboud University Medical Centre

    Nijmegen, Netherlands

  • St. Antonius Hospital

    Nieuwegein, Netherlands

  • University Medical Centre Groningen

    Groningen, Netherlands

  • University Medical Centre Utrecht

    Utrecht, Netherlands

  • Ziekenhuis Oost-Limburg

    Genk, Flanders, 3600, Belgium

Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal adenocarcinoma colorectal cancer colorectal carcinoma colorectal neoplasm Hyperthermia peritoneal carcinomatosis peritoneal neoplasm peritoneum cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.