Can vitamins boost gum bone healing? new study tests simple addition to standard treatment
NCT ID NCT05499598
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding vitamins A and C to a platelet-rich fibrin (PRF) treatment helps repair bone defects in the gums. Twenty-eight adults with advanced gum disease received a minimally invasive surgical technique with PRF, with or without the vitamins. The goal was to see if the vitamin mix improves bone fill and gum attachment over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Platelet-rich fibrin with vitamins A and C
- What this could lead to
- If it works, this could offer a better way to repair gum bone damage and improve dental health without major surgery.
- What could go wrong
- This is a small, early-stage trial with only 28 participants, so results may not apply to everyone. Adding vitamins may not provide extra benefit over standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo University
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Gentler gum surgery could repair deep defects without cutting the gums
- First days after gum surgery may predict Year-Long success
- Gentler mouthwash could tame gum disease with fewer side effects