Could a common drug plus a supplement help men with infertility?

NCT ID NCT07252518

Recruiting now Disease control Sponsor: Mst.Sumyara Khatun Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking pentoxifylline (a drug that improves blood flow) together with coenzyme Q10 (a natural supplement) can increase sperm movement better than CoQ10 alone. Fifty-six men with low sperm motility will take either the combo or just CoQ10 for three months. The goal is to see if the combination leads to more progressive sperm movement, which could improve fertility.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pentoxifylline and coenzyme Q10
What this could lead to: If it works, this could offer a simple, low-cost combination therapy to improve sperm motility in men with low sperm movement.
What could go wrong: This is a small, early-stage trial with only 56 participants, so results may not apply widely. The treatment may not work better than CoQ10 alone, and pentoxifylline can cause side effects like nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Asthenozoospermia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHENOZOOSPERMIA

Contacts and locations

Locations

Bangladesh Medical University
RECRUITING

Dhaka, Shahbag, 1000, Bangladesh

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