New combo therapy aims to boost immune attack on aggressive prostate cancer

NCT ID NCT05568550

First seen Jan 31, 2026 · Last updated May 15, 2026 · Updated 16 times

Summary

This study tests whether adding immunotherapy (pembrolizumab) and a PARP inhibitor (olaparib) to standard radiation can better control high-risk prostate cancer. About 64 men with localized but aggressive prostate cancer will receive these treatments. The goal is to see if the combination leads to very low PSA levels after treatment and improves long-term outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huntsman Cancer Institute

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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