New combo therapy shows promise for tough esophageal cancer

NCT ID NCT02642809

First seen Mar 23, 2026 · Last updated May 07, 2026 · Updated 6 times

Summary

This early-phase study tested a new approach for people with metastatic esophageal cancer (cancer that has spread). It combined a short, strong dose of internal radiation (brachytherapy) with the immunotherapy drug pembrolizumab. The goal was to see if the radiation could help the immune system fight the cancer better. The study involved 16 participants and focused mainly on safety and tumor changes.

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Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.