Tailored blood flow during surgery cuts deadly complications in High-Risk patients

NCT ID NCT05648279

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 21 times

Summary

This study tested whether giving each patient a personalized blood flow target during major abdominal surgery could lower the risk of serious complications like kidney injury, heart damage, infections, and death. Over 1,100 high-risk adults (aged 45+) took part. The approach used each patient's own pre-surgery heart function as a guide, rather than a one-size-fits-all target.

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Contacts and locations

Locations

  • Clínica Universidad de Navarra

    Pamplona, Spain

  • Hvidovre Hospital

    Copenhagen, Denmark

  • LMU Munich

    Munich, Germany

  • Medical University of Graz

    Graz, Austria

  • Rigshospitalet

    Copenhagen, Denmark

  • University Hospital Düsseldorf

    Düsseldorf, Germany

  • University Hospital Marburg

    Marburg, Germany

  • University Hospital Plzen

    Pilsen, Czechia

  • University Hospital RWTH Aachen

    Aachen, Germany

  • University Medical Center Copenhagen Bispebjerg and Frederiksberg

    Copenhagen, Denmark

  • University Medical Center Hamburg

    Hamburg, Germany

  • University Medical Center Schleswig Holstein, Lübeck

    Lübeck, Germany

Conditions

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