Can a gout drug protect kidneys in cancer patients?
NCT ID NCT04745910
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested pegloticase, a drug used for gout, in 10 cancer patients with high uric acid from tumor lysis syndrome. The goal was to see if it could quickly lower uric acid levels and protect kidney function. It was a small pilot trial to gather early data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pegloticase (a drug that breaks down uric acid)
What this could lead to
If it works, this could offer a new way to quickly lower uric acid and protect kidney function in cancer patients with tumor lysis syndrome.
What could go wrong
This is a very small pilot study with only 10 participants, so results may not apply to everyone. The drug may not work as expected or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States