Tumor lysis syndrome
MONDO:0043875A condition of metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. Tumor lysis syndrome typically occurs in aggressive, rapidly proliferating lymphoproliferative disorders. Burkitt lymphoma and T cell acute lymphoblastic leukemia are commonly associated with this syndrome. Metabolic abnormalities include hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia and may result in renal failure, multiple organ failure, and death.
Also known as: tumor lysis syndrome, syndrome, tumor lysis, syndrome, tumour lysis, syndromes, tumor lysis, syndromes, tumour lysis
6 clinical trials for this condition and its sub-types.
Follow this condition to get notified about new trialsBroader categories
-
New pill ZE50-0134 takes on Hard-to-Treat leukemia and lymphoma
Disease control Recruiting nowThis early-stage study is testing a new oral drug called ZE50-0134 in 66 adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or certain low-grade lymphomas that have come back or not responded to prior treatments. The main goal is to check the drug's…
Phase 1 • Sponsor: Lomond Therapeutics Holdings, Inc. • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
-
Timing is everything: new study seeks optimal moment for dialysis in cancer-related kidney failure
Knowledge-focused Recruiting nowThis study examines whether starting kidney dialysis early or later improves outcomes for patients with tumor lysis syndrome, a complication of cancer treatment that can cause acute kidney injury. Researchers will review data from 800 adults treated in ICUs between 2013 and 2023.…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC