Electric pulses aim to zap breast cancer tumors in early safety trial

NCT ID NCT07487844

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This pilot study tests a device that uses short, high-frequency electrical pulses to shrink or destroy soft tissue tumors in people with metastatic breast cancer. The trial will enroll 20 adults with tumors near the skin that are at least 1 cm but no larger than 5 cm. The main goal is to check safety, and researchers will also track quality of life using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pulsed Electric Field (PEF) System (Aliya™ PEF System)
What this could lead to
If it works, this could offer a new, non-invasive way to shrink or destroy superficial tumors in metastatic breast cancer, potentially improving local control and quality of life.
What could go wrong
This is a very early, small pilot study (20 people) focused on safety, not effectiveness. The treatment is limited to superficial lesions, and it may not shrink tumors or improve survival. Side effects are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

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