Light therapy shows promise against HPV-Linked cervical precancer

NCT ID NCT07306247

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a treatment called photodynamic therapy (PDT) for women with low-grade cervical precancer caused by HPV types 16 or 18. A photosensitizing cream is applied to the cervix, then activated with light to destroy abnormal cells. The trial will compare 225 women who receive PDT to those who are simply observed, tracking whether the virus clears and the cervical tissue returns to normal over 24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aminolevulinic acid (ALA) used in photodynamic therapy (PDT)

What this could lead to

If successful, this could offer a non-surgical treatment option for cervical precancer caused by high-risk HPV types 16 and 18.

What could go wrong

This is an early-stage, non-randomized study with no control group, so results may not be definitive. The treatment requires multiple sessions and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical squamous intraepithelial neoplasia human papilloma virus infection Squamous Intraepithelial Lesions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Ningbo University

    Ningbo, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • First People's Hospital of Hangzhou

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-••••

  • Hangzhou Linping District first People's Hospital

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shaoxing People's Hospital

    Shaoxing, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Women's Hospital School Of Medicine Zhejiang University

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••