Light therapy could replace surgery for cervical precancer
NCT ID NCT07306260
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a light-activated gel treatment (ALA-PDT) to standard surgery (LEEP) for women with high-grade cervical precancer (HSIL/CIN2). About 560 women will receive either the gel plus red light therapy or surgery. The goal is to see if the gel treatment works as well as surgery, with fewer side effects and less impact on fertility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ALA-PDT (aminolevulinic acid photodynamic therapy)
What this could lead to
If it works, this could offer a less invasive, tissue-sparing alternative to surgery for treating cervical precancerous lesions, potentially reducing side effects and preserving fertility.
What could go wrong
This is a non-randomized study, so results may be less reliable. The treatment requires multiple sessions, and it may not be as effective as surgery in the long term. HPV clearance is not guaranteed.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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First People's Hospital of Hangzhou
Hangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hangzhou Linping District first People's Hospital
Hangzhou, Zhejiang, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shaoxing People's Hospital
Shaoxing, Zhejiang, China
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Women's Hospital School Of Medicine Zhejiang University
Hangzhou, Zhejiang, 310000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••