Heart transplant patients get new weapon against hidden artery damage

NCT ID NCT03537742

First seen Apr 19, 2026 · Last updated May 27, 2026 · Updated 5 times

Summary

This study tested the drug alirocumab in 114 heart transplant recipients to see if it could slow or prevent a common complication called cardiac allograft vasculopathy (CAV), where the heart's blood vessels narrow. Participants received the drug soon after transplant, and researchers measured changes in plaque buildup in the coronary arteries using ultrasound. The goal was to see if lowering cholesterol with this drug could protect the new heart from vessel damage.

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Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94305, United States

Conditions

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