Heart transplant patients may soon skip invasive artery checks with new PET scan study
NCT ID NCT06089486
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a non-invasive PET scan can safely replace the standard invasive coronary angiography for monitoring heart transplant patients. About 576 participants who had a heart transplant 2-10 years ago will be randomly assigned to annual surveillance with either PET or angiography. The goal is to see if PET is just as good at detecting dangerous artery narrowing without the risks of an invasive procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If PET proves as effective as invasive angiography, heart transplant patients could avoid repeated invasive procedures for routine monitoring.
What could go wrong
This is a non-inferiority trial, so PET might not be as accurate as angiography. The study is observational in design, not testing a new treatment.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARDIAC ALLOGRAFT VASCULOPATHY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Mazankowski Alberta Heart Institute
NOT_YET_RECRUITINGEdmonton, Alberta, Canada
Contact
-
Montreal Heart Institute
NOT_YET_RECRUITINGMontreal, Quebec, Canada
Contact
-
Toronto-General Hospital - University Health Network
NOT_YET_RECRUITINGToronto, Ontario, Canada
Contact
-
University of Calgary
NOT_YET_RECRUITINGCalgary, Alberta, Canada
Contact
-
University of Ottawa Heart Institute
RECRUITINGOttawa, Ontario, K1Y 4W7, Canada
Contact