New DNA test could beat old method for stubborn UTIs
NCT ID NCT06996301
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study tested whether a DNA-based PCR test works better than the usual lab culture for diagnosing complicated urinary tract infections (cUTIs) in adults. Over 770 participants across six U.S. sites were randomly assigned to have their treatment guided by either PCR or culture results. The goal was to see which method leads to more patients getting better by day 28, and whether PCR can help reduce unnecessary antibiotic use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PCR diagnostic test (DocLab UTM 2.0)
What this could lead to
If PCR proves more accurate or faster than standard culture, it could help doctors choose the right antibiotic sooner, reducing ineffective treatment and antibiotic resistance.
What could go wrong
The trial is completed but results are not yet reported; PCR may not show a clear advantage over culture, and its higher cost or complexity could limit real-world use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Albany Urology Clinic & Surgery Center
Albany, Georgia, 31707, United States
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Augusta Urology Associates
Evans, Georgia, 30809, United States
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Colquitt Regional Medical Center
Moultrie, Georgia, 31768, United States
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Norman Urology Associates
Norman, Oklahoma, 73071, United States
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Phoenix Urology of St Joseph
Saint Joseph, Missouri, 64506, United States
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Silicon Valley Medical Development
San Jose, California, 95124, United States