Can pressurized oxygen ease bladder damage from radiation?
NCT ID NCT07368647
First seen Jun 25, 2026 · Last updated Jul 14, 2026 · Updated 3 times
Summary
This study looks at how hyperbaric oxygen therapy (HBOT) affects symptoms and urine markers in people with chronic radiation cystitis, a bladder condition caused by past radiation treatment. Researchers will collect urine, blood, and tissue samples from 100 participants before, during, and after HBOT. The goal is to understand if HBOT can reduce symptoms like blood in the urine and lower the risk of urinary tract infections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber)
- What this could lead to
- If successful, this could show that hyperbaric oxygen therapy improves symptoms and reduces urinary tract infections in people with radiation cystitis.
- What could go wrong
- This is an early-stage observational study with only 100 participants, so results may not apply to everyone. It is not designed to prove the therapy works, only to gather data.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dartmouth-Hitchcock Medical Center
RECRUITINGLebanon, New Hampshire, 03756, United States
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