Brain zapping gets personal: new hope for Treatment-Resistant depression?
NCT ID NCT05842291
First seen May 07, 2026
Summary
This study tests a personalized form of brain stimulation (rTMS) for people with depression that hasn't improved with standard treatments. Sixty participants will receive either real or sham stimulation over five days, with up to ten sessions per day. The goal is to see if targeting specific brain areas based on each person's brain activity can safely reduce depression symptoms.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beijing HuiLongGuan Hospital
Beijing, Beijing Municipality, 100096, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
repetitive transcranial magnetic stimulation (rTMS) using personalized brain targets
What this could lead to
If it works, this could offer a new, non-drug option for people with depression that hasn't responded to other treatments.
What could go wrong
This is a small, early-stage trial that is currently suspended. The effect may be small or no better than sham, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.