Brain zapping gets personal: new hope for Treatment-Resistant depression?

NCT ID NCT05842291

Terminated Disease control Sponsor: Changping Laboratory Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a personalized form of brain stimulation (rTMS) for people with depression that hasn't improved with standard treatments. Sixty participants will receive either real or sham stimulation over five days, with up to ten sessions per day. The goal is to see if targeting specific brain areas based on each person's brain activity can safely reduce depression symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) using personalized brain targets
What this could lead to: If it works, this could offer a new, non-drug option for people with depression that hasn't responded to other treatments.
What could go wrong: This is a small, early-stage trial that is currently suspended. The effect may be small or no better than sham, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TREATMENT RESISTANT DEPRESSION

Contacts and locations

Locations

Beijing HuiLongGuan Hospital

Beijing, Beijing Municipality, 100096, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.