Parental distress may undermine treatment in children with recurrent brain tumors

NCT ID NCT07660458

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether the emotional distress of parents—such as depression, anxiety, or trauma—affects how well children with recurrent medulloblastoma follow their treatment plans. Researchers will follow 450 parent-child pairs across four hospitals, measuring parental distress through questionnaires and tracking treatment adherence over 12 months. The goal is to identify which types of distress most strongly predict poor adherence, which could inform future support programs for families facing this devastating disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If parental distress is found to predict poor adherence, this could lead to targeted psychological support programs for caregivers, potentially improving treatment outcomes for children.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The results may not apply to all families, and other factors could influence adherence.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • West China Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

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